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The erythropoietic porphyrias primarily influence the skin, which often can bring about photosensitivity, blisters, itching, and swelling, and enhanced hair development on areas such as the forehead. In several of my sorts, accumulated heme precursors excreted from the urine may transform its colour; One example is following exposure to daylight, I'm able to alter your urine to your darkish reddish or dim brown shade.